Open the glove box to the Lexus and remove all of its contents.
Locate the glove-box stop on the bottom right-hand side of the glove box and remove the screw with the screwdriver. This will allow the glove box to dangle.
Behind the open area where the glove box was, look for the end of a white filter frame with release tabs on either side.
Move the dangling wire harness to the left to get it out of the way.
Push the tabs on both sides of the filter frame and pull it straight out.
Remove the old filter and discard.
Insert the new filter and tuck it into the tabs on both sides of the filter frame.
Slide the filter frame back into its cavity until the release tabs lock into place.
Replace the wire harness in its original position.
Lift the glove box and support it in an open position while replacing the screw into the designated hole for the glove-box stop.
Return the contents to the glove box.Maybe you've never before heard of a cabin air filter. They're fairly new, but found in many vehicles now being manufactured. They're as important to replace as the engine air filter, to prohibit pollutants and allergens from contaminating the interior cab of your Lexus. Replacing them is not all that difficult once you've determined where they are. Some dealerships will charge outrageous prices to replace them, when all you need is a Phillips-head screwdriver and about 10 to 15 minutes' worth of time to learn to do it. Once you've figured it out, you'll be able to replace the next one in half that time.